USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: Q15233 USC-OGP 2-DE database:  Q15233 Q15233 General information about the entry View entry in simple text format Entry name NONO_HUMAN Primary accession number Q15233 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Non-POU domain-containing octamer-binding protein; Short=NonO protein; AltName: Full=54 kDa nuclear RNA-and DNA-binding protein; AltName: Full=55 kDa nuclear protein; AltName: Full=DNA-binding p52/p100 complex, 52 kDa subunit; AltName: Full=NMT55; AltName: Full=p54(nrb); Short=p54nrb;. Gene name Name=NONO Synonyms=NRB54 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1146: pI=5.35; Mw=57061 Cross-references UniProtKB/Swiss-Prot Q15233; NONO_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name NONO_HUMAN Primary accession number Q15233 Secondary accession number(s) B7Z4C2 D3DVV4 F5GYZ3 O00201 P30807 Q12786 Q9BQC5 Sequence was last modified on  July 5, 2005 (version 4) Annotations were last modified on  March 15, 2017 (version 183) Name and origin of the protein Description RecName: Full=Non-POU domain-containing octamer-binding protein; Short=NonO protein; AltName: Full=54 kDa nuclear RNA-and DNA-binding protein; AltName: Full=55 kDa nuclear protein; AltName: Full=DNA-binding p52/p100 complex, 52 kDa subunit; AltName: Full=NMT55; AltName: Full=p54(nrb); Short=p54nrb; Gene name Name=NONO Synonyms=NRB54 Encoded on Name=NONO; Synonyms=NRB54 Keywords 3D-structure; Acetylation; Activator; Alternative splicing; Biological rhythms; Chromosomal rearrangement; Coiled coil; Complete proteome; Direct protein sequencing; DNA damage; DNA recombination; DNA repair; DNA-binding; Isopeptide bond; Mental retardation; Methylation; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Repeat; Repressor; RNA-binding; Transcription; Transcription regulation; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL L14599; AAC37578.1; -; mRNA EMBL U89867; AAC51852.1; -; mRNA EMBL Y11289; CAA72157.1; -; Genomic_DNA EMBL Y11290; CAA72157.1; JOINED; Genomic_DNA EMBL Y11291; CAA72157.1; JOINED; Genomic_DNA EMBL Y11292; CAA72157.1; JOINED; Genomic_DNA EMBL Y11293; CAA72157.1; JOINED; Genomic_DNA EMBL Y11294; CAA72157.1; JOINED; Genomic_DNA EMBL Y11295; CAA72157.1; JOINED; Genomic_DNA EMBL Y11296; CAA72157.1; JOINED; Genomic_DNA EMBL Y11297; CAA72157.1; JOINED; Genomic_DNA EMBL Y11298; CAA72157.1; JOINED; Genomic_DNA EMBL U02493; AAA03427.1; -; mRNA EMBL AK297144; BAH12508.1; -; mRNA EMBL CR456761; CAG33042.1; -; mRNA EMBL AL590762; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471132; EAX05298.1; -; Genomic_DNA EMBL CH471132; EAX05299.1; -; Genomic_DNA EMBL CH471132; EAX05300.1; -; Genomic_DNA EMBL BC002364; AAH02364.1; -; mRNA EMBL BC003129; AAH03129.1; -; mRNA EMBL BC012141; AAH12141.1; -; mRNA EMBL BC028299; AAH28299.1; -; mRNA EMBL BC069616; AAH69616.1; -; mRNA EMBL BC069639; AAH69639.1; -; mRNA CCDS CCDS14410.1; -. [Q15233-1]; . CCDS CCDS55445.1; -. [Q15233-2]; . PIR G01211; G01211; . PIR S29769; S29769; . PIR S41768; S41768; . RefSeq NP_001138880.1; NM_001145408.1. [Q15233-1]; . RefSeq NP_001138881.1; NM_001145409.1. [Q15233-1]; . RefSeq NP_001138882.1; NM_001145410.1. [Q15233-2]; . RefSeq NP_031389.3; NM_007363.4. [Q15233-1]; . UniGene Hs.533282; -; . UniGene Hs.700344; -; . PDB 3SDE; X-ray; 1.90 A; B=53-312 PDB 5IFM; X-ray; 2.60 A; A/B/C/D/E/F/G/H/I/J/K/L=53-312 PDBsum 3SDE; -; . PDBsum 5IFM; -; . ProteinModelPortal Q15233; -; . SMR Q15233; -; . BioGrid 110904; 167; . DIP DIP-29951N; -; . IntAct Q15233; 51; . MINT MINT-1131452; -; . STRING 9606.ENSP00000276079; -; . iPTMnet Q15233; -; . PhosphoSitePlus Q15233; -; . SwissPalm Q15233; -; . BioMuta NONO; -; . DMDM 67469924; -; . REPRODUCTION-2DPAGE IPI00304596; -; . SWISS-2DPAGE Q15233; -; . EPD Q15233; -; . MaxQB Q15233; -; . PaxDb Q15233; -; . PeptideAtlas Q15233; -; . PRIDE Q15233; -; . TopDownProteomics Q15233-1; -. [Q15233-1]; . DNASU 4841; -; . Ensembl ENST00000276079; ENSP00000276079; ENSG00000147140. [Q15233-1]; . Ensembl ENST00000373841; ENSP00000362947; ENSG00000147140. [Q15233-1]; . Ensembl ENST00000373856; ENSP00000362963; ENSG00000147140. [Q15233-1]; . Ensembl ENST00000535149; ENSP00000441364; ENSG00000147140. [Q15233-2]; . GeneID 4841; -; . KEGG hsa:4841; -; . UCSC uc004dzn.5; human. [Q15233-1]; . CTD 4841; -; . DisGeNET 4841; -; . GeneCards NONO; -; . HGNC HGNC:7871; NONO; . HPA CAB022069; -; . HPA HPA054094; -; . HPA HPA054559; -; . MalaCards NONO; -; . MIM 300084; gene; . MIM 300967; phenotype; . neXtProt NX_Q15233; -; . OpenTargets ENSG00000147140; -; . Orphanet 319308; Translocation renal cell carcinoma; . PharmGKB PA31680; -; . eggNOG KOG0115; Eukaryota; . eggNOG ENOG410XQA0; LUCA; . GeneTree ENSGT00390000005004; -; . HOGENOM HOG000231095; -; . HOVERGEN HBG009801; -; . InParanoid Q15233; -; . KO K13214; -; . OMA NQQYHKE; -; . OrthoDB EOG091G09T7; -; . PhylomeDB Q15233; -; . TreeFam TF315795; -; . SIGNOR Q15233; -; . GeneWiki NONO; -; . GenomeRNAi 4841; -; . PMAP-CutDB Q15233; -; . PRO PR:Q15233; -; . Proteomes UP000005640; Chromosome X; . Bgee ENSG00000147140; -; . CleanEx HS_NONO; -; . ExpressionAtlas Q15233; baseline and differential; . Genevisible Q15233; HS; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0016363; C:nuclear matrix; IDA:BHF-UCL; . GO GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell; . GO GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0005634; C:nucleus; ISS:UniProtKB; . GO GO:0042382; C:paraspeckles; IDA:MGI; . GO GO:0090575; C:RNA polymerase II transcription factor complex; ISS:BHF-UCL; . GO GO:0003682; F:chromatin binding; ISS:BHF-UCL; . GO GO:0001047; F:core promoter binding; ISS:UniProtKB; . GO GO:0042802; F:identical protein binding; IPI:IntAct; . GO GO:0000166; F:nucleotide binding; IEA:InterPro; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; ISS:BHF-UCL; . GO GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IBA:GO_Central; . GO GO:0007623; P:circadian rhythm; ISS:UniProtKB; . GO GO:0006310; P:DNA recombination; IEA:UniProtKB-KW; . GO GO:0006281; P:DNA repair; IEA:UniProtKB-KW; . GO GO:0006397; P:mRNA processing; TAS:ProtInc; . GO GO:0000398; P:mRNA splicing; via spliceosome; IBA:GO_Central GO GO:1903377; P:negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway; IDA:ParkinsonsUK-UCL; . GO GO:0045892; P:negative regulation of transcription; DNA-templated; ISS:UniProtKB GO GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB; . GO GO:0006355; P:regulation of transcription; DNA-templated; IBA:GO_Central GO GO:0008380; P:RNA splicing; TAS:ProtInc; . GO GO:0006351; P:transcription; DNA-templated; IEA:UniProtKB-KW Gene3D 3.30.70.330; -; 2; . InterPro IPR012975; NOPS; . InterPro IPR012677; Nucleotide-bd_a/b_plait; . InterPro IPR000504; RRM_dom; . Pfam PF08075; NOPS; 1; . Pfam PF00076; RRM_1; 2; . SMART SM00360; RRM; 2; . SUPFAM SSF54928; SSF54928; 1; . PROSITE PS50102; RRM; 2; .

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